1. Improves sleep

According to the Division of Sleep Medicine, Brigham and Women’s Hospital, Harvard school of medicine, patients with primary insomnia have 30 percent lower GABA levels (3).

Research has shown that GABA can play an important role in improving sleep quality and duration.

It is well established that activation of GABA(A) receptors favor sleep (4). GABA features a sedative effect which naturally induces sleep.

According to one 2005 study published within the Journal of Nutritional Science and Vitaminology, simultaneous intake of GABA and AVLE shortened sleep latency by 4.3 minutes and increased non-REM sleep time by 5.1 % (5).

In fact, supplementation with GABA extracts also can help counter sleep disturbance induced by caffeine (6).

  1. Helps affect depression

People that are diagnosed with depression typically have low levels of GABA (7). Treatment of depression also improves GABA levels.

According to a study published within the American Journal of Psychiatry, when patients with severe depression underwent a course of electroshock (ECT), there was a big increase in their occipital cortex GABA concentrations (8).

Thanks to its antidepressant properties, GABA could also be an efficient treatment for depression.

  1. Relief from PMS

The PMS refers to a gaggle of symptoms like anxiety, insomnia, mood swing, and cravings that affect women before menstruation. consistent with research, GABA levels are disrupted by menstruation, and that they decline during the cycle (9).

Research seems to suggest that GABA is often wont to provide relief from the symptoms of PMS. Various studies have shown that GABA is often wont to provide relief from pain and muscle cramps (10, 11).

  1. Improves ADHD

Attention deficit hyperactivity disorder (ADHD) is characterized by symptoms like impulsivity, hyperactivity, and difficulty in concentrating. Studies have found that children with ADHD have lower levels of GABA concentration.

A study from The Johns Hopkins University of drugs, Baltimore, found that GABA concentration is reduced in children with ADHD as compared to typically developing control subjects (12).

Taking GABA supplements alongside the normal treatment for ADHD can help improve the symptoms.

  1. Helps decrease inflammation

In addition to its anti-anxiety properties, GABA also helps in inhibiting inflammation. Chronic inflammation can cause diseases like cancer, arthritis, and even heart condition. So, GABA could also be helpful within the treatment of those diseases.

According to a 2011 animal-based study, when researchers gave GABA supplements to mice, it reduced the danger of developing rheumatic arthritis, and therefore the mice that did develop arthritis had milder symptoms (13).